Table of Contents
What is the survival rate for acute promyelocytic leukemia?
APL is now considered a highly curable disease, with 2-year event-free survival rates of 75–84\%. Early mortality is common in APL and is frequently related to hemorrhagic complications.
Is APL leukemia rare?
APL is a relatively rare type of leukemia that causes a buildup of immature white blood cells in your blood and bone marrow.
Can leukemia be caused by stress?
Clinical and epidemiological studies have shown that stress-related biobehavioral factors are associated with accelerated progression of several types of cancer, including solid epithelial tumors and hematopoietic tumors such as leukemia (Antoni et al., 2006; Chida et al., 2008).
Is Apml genetic?
Acute promyelocytic leukemia is not inherited but arises from a translocation in the body’s cells that occurs after conception.
How long can you live with APL leukemia?
Currently large cohort of patients enjoys disease-free survival of 5 years or longer. However, a disease-free status is not synonymous with a life free of physical and psychological health related to the cancer and/or its treatment.
Is promyelocytic leukemia hereditary?
What gender does leukemia affect the most?
Gender: Men are more likely than woman to develop leukemia. Age: The risk of most leukemias increase with age. The median age of a patient diagnosed with acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) or chronic myeloid leukemia (CML) is 65 years and older.
What is a promyelocytic leukemia?
Acute promyelocytic leukemia (APL) is a blood cancer characterized by a marked increase in a type of white blood cells known as promyelocytes, a type of immature white blood cell. It develops in about 600 to 800 individuals each year in the United States, most often in adults around the age of 40.
What are the risk factors for acute myeloid leukemia?
Exposure to cancer-causing agents. People exposed to high doses of radiation (from the explosion of an atomic bomb,working in an atomic weapons plant,or a nuclear reactor accident) have
What causes APL leukemia?
APL is due to a translocation (an exchange of chromosome material) between chromosomes 15 and 17 which is symbolized t(15;17). This translocation is not a mere marker of APL. It is the cause of APL. APL was first recognized as a distinct disease entity in 1957. It accounts for 5-10\% of cases of acute myeloid leukemia (AML).
What are the symptoms of chronic leukemia?
Painless swelling of the lymph nodes in the neck,underarm,stomach,or groin
Is acute myelogenous leukemia curable?
Leukemia – Acute Myeloid – AML: Statistics. Although AML is a serious disease, it is treatable and often curable with chemotherapy with or without a bone marrow/stem cell transplant (see the Types of Treatment section).