Table of Contents
What is the half-life of vitamin D supplement?
Calcitriol (1,25-dihydroxyvitamin D3), the active form of vitamin D, has a half-life of about 15 hours, while calcidiol (25-hydroxyvitamin D3) has a half-life of about 15 days.
Can I take vitamin D only once a week?
Oral vitamin D3 can be taken once a day but also with longer intervals because of its long half life, being around 25 days. It is not known whether equivalent doses once a week or once a month are equally effective.
What is the half-life of 25 hydroxyvitamin D?
approximately 3 weeks
The half-life of 25-OHD is approximately 3 weeks, this is in contrast to the half-life of the parent vitamin D which is 24 hours and the half-life of 1,25(OH)2D which is of the order 4-6 hours.
What is the half-life of vitamin D?
Half-life of vitamin D varies Vitamin D Half-Life is ‘1-6 weeks” Half-life: the time till half of the quantity still exists Example: Start with 30 ng of vitamin D and half-life of 6 weeks, then 15 ng at 6 weeks
What is a good level of vitamin D deficiency?
In 2010, the venerable Institute of Medicine (IOM) issued a report based on lengthy examination of data by a group of experts. To sum up, they estimated that a vitamin D level of 20 ng/mL or higher was adequate for good bone health, and subsequently a level below 20 was considered a vitamin D deficiency.
Should the IOM cutoff for vitamin D be lowered to 20?
In this piece, several of the leading epidemiologists and endocrinologists who were on the original IOM committee argue for a lowering of the currently accepted cutoff level of 20, stating that the level they estimated as acceptable was never intended to be used to define vitamin D deficiency.
How fast do vitamin D levels change with vitamin D supplementation?
In an analysis by Heaney et al., the following chart shows that in response to daily supplementation (4000, 5500, or 11,000 IU/day), serum vitamin D3 increased rapidly during the first week, then declined and plateaued around 3 weeks, with continued variation until about day 60 (2 months). What about changes in the 25 (OH) vitamin D level?