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What can happen to the red blood cells when a hypertonic solution is administered intravenously?
A hypertonic solution causes water to move out of cells. This would cause the red blood cells to undergo crenation, also leading to cell death (same final outcome as hemolysis – impaired gas transport).
How does tonicity affect red blood cells?
The tonicity of the urea and resultant osmotic water movement results in hemolysis of the cells, and this will form the blood used for the production of the hemoglobin standards that will be used to assess the degree of hemolysis in the experiment.
What are the effects of tonicity on cells?
The tonicity of a solution is related to its effect on the volume of a cell. Solutions that do not change the volume of a cell are said to be isotonic. A hypotonic solution causes a cell to swell, whereas a hypertonic solution causes a cell to shrink.
What does saline solution do to red blood cells?
Infusion of normal saline in high volumes during resuscitation and apheresis can cause hyperchloremic metabolic acidosis, which may impair the renal function. Normal saline is also commonly used as an isotonic buffer for red blood cells in research protocols.
Why do intravenous IV solutions need to have the same tonicity as blood?
It is important for IV to be isotonic to your blood so it doesn’t change the concentration of different molecules in the bloodstream. the cell wall will start to shrink, due to loss of the fluid. High osmotic pressure with allow fluids to pull fluids out of the cell.
What is the effect of injecting hypertonic and hypotonic solution intravenously?
It was shown that such administration of strongly hypertonic solutions markedly lowered the pressure of the cerebrospinal fluid, frequently producing negative values; with hypotonic solutions (distilled water) a prolonged rise in the pressure of the fluid was obtained.
How does tonicity affect the movement of water in cells?
Tonicity in living systems If a cell is placed in a hypertonic solution, water will leave the cell, and the cell will shrink. In an isotonic environment, there is no net water movement, so there is no change in the size of the cell.
What is the tonicity of a solution?
“Tonicity is the ability of a solution to affect the fluid volume and pressure in a cell. If a solute cannot pass through a plasma membrane, but remains more concentrated on one side of the membrane than on the other, it causes osmosis.”
What is the tonicity of the solution?
In biology, the tonicity of a solution usually refers to its solute concentration relative to that of another solution on the opposite side of a cell membrane; a solution outside of a cell is called hypertonic if it has a greater concentration of solutes than the cytosol inside the cell.
What caused the RBC to react differently in the different solutions?
Mammalian red blood cells have a biconcave (doughnut-like) shape. If red blood cells are placed in a solution with a lower solute concentration than is found in the cells, water moves into the cells by osmosis, causing the cells to swell; such a solution is hypotonic to the cells. …
Why is it important that this solution be of the same concentration as that of blood plasma?
During intravenous injections, the concentrations of the solution to be injected should be comparable to blood plasma. If the solution is less concentrated, its osmotic pressure will be low. The water will try to move into the red blood cells through the cell walls. As a result, cells will swell and burst.