Is curcumin a carcinogen?
This seems to indicate that curcumin is a pharmacologically safe agent that may be used in cancer chemoprevention and therapy. Both in vitro and in vivo studies have shown, however, that curcumin may produce toxic and carcinogenic effects under specific conditions.
Is it safe to take curcumin long-term?
High doses of turmeric and curcumin are not recommended long-term since research confirming their safety is lacking. However, the World Health Organization (WHO) has determined 1.4 mg per pound (0–3 mg/kg) of body weight an acceptable daily intake ( 18 ).
Why is curcumin bad?
A small percentage of people experience stomach upset, gastroesophageal reflux disease, nausea, dizziness, or diarrhea from taking curcumin supplements, particularly if taken regularly at too-high doses. A few doctors have expressed concern over excessive dosing as well as long-term safety.
Is curcumin a form of estrogen?
Recent research proved that curcumin, acting as a phytoestrogen, competitively inhibited endogenous estrogen, which also contributed to the suppression of breast cancer cell growth. Furthermore, curcumin suppresses breast cancer proliferation partially due to other trophic signaling pathways.
Does curcumin raise estrogen?
Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Turmeric contains a chemical called curcumin, which might act like the hormone estrogen. In theory, this might have effects on hormone-sensitive conditions.
Is turmeric bad for your liver?
The authors concluded that pure turmeric could directly lead to liver damage but stated that unknown contaminants causing hepatic injury could not be excluded.
Does turmeric raise estrogen levels?
Turmeric contains a chemical called curcumin. A 2013 study indicated that curcumin may reduce estrogen levels.
Does curcumin block estrogen?